Melanoma-Associated Spongiform Scleropathy in Oculodermal Melanocytosis with Primary Orbital Melanoma


Journal Article

© 2016 S. Karger AG, Basel. Purpose: To describe spongiform scleropathy in a patient with oculodermal melanosis and without evidence of uveal melanoma. Methods: Clinical-pathological correlation conducted in compliance with HIPPA (Health Insurance Privacy and Portability Act) regulations. Results: Melanoma-associated spongiform scleropathy was an incidental finding in an 87-year-old woman with oculodermal melanocytosis treated for primary orbital melanoma. All previously reported cases of this scleropathy have been associated with uveal melanoma. Conclusions: The mechanism of scleral degeneration in melanoma-associated spongiform scleropathy is unknown, and its clinical and prognostic significance is speculative. This is the first case of a so-called melanoma-associated spongiform scleropathy reported in an eye without uveal melanoma.

Full Text

Duke Authors

Cited Authors

  • Ranjit, RU; Leyngold, IM; Margo, CE

Published Date

  • 2016-10-01

Published In

Volume / Issue

  • 2 / 4

Start / End Page

  • 276 - 279

Electronic International Standard Serial Number (EISSN)

  • 2296-4657

International Standard Serial Number (ISSN)

  • 2296-4681

Digital Object Identifier (DOI)

  • 10.1159/000447595

Citation Source

  • Scopus