Open Source Closed-Loop Insulin Delivery Systems: A Clash of Cultures or Merging of Diverse Approaches?

Journal Article (Journal Article)

Biomedical outcomes for people with diabetes remain suboptimal for many. Psychosocial care in diabetes does not fare any better. "Artificial pancreas" (also known as "closed-loop" and "automated insulin delivery") systems present a promising therapeutic option for people with diabetes (PWD)-simultaneously improving glycemic outcomes, reducing the burden of self-management, and improving health-related quality of life. In recent years there has emerged a growing movement of PWD innovators rallying behind the mantra #WeAreNotWaiting, developing "do-it-yourself artificial pancreas systems (DIY APS)." Self-reported results by DIY APS users show improved metabolic outcomes such as impressive stability of glucose profiles, significant reduction of A1c, and more time within their glycemic target range. However, the benefits remain unclear for the broader population of PWD beyond these highly engaged, highly tech-savvy users willing and able to engage in the demands of building and maintaining their DIY APS. We discuss the challenges faced by key stakeholder groups in terms of potential collaboration and open debate of these challenges.

Full Text

Duke Authors

Cited Authors

  • Barnard, KD; Ziegler, R; Klonoff, DC; Braune, K; Petersen, B; Rendschmidt, T; Finan, D; Kowalski, A; Heinemann, L

Published Date

  • November 2018

Published In

Volume / Issue

  • 12 / 6

Start / End Page

  • 1223 - 1226

PubMed ID

  • 30079769

Pubmed Central ID

  • PMC6232748

Electronic International Standard Serial Number (EISSN)

  • 1932-2968

Digital Object Identifier (DOI)

  • 10.1177/1932296818792577


  • eng

Conference Location

  • United States