Sclerosing Cholangitis-Like Changes on Magnetic Resonance Cholangiography in Patients With Drug Induced Liver Injury.


Journal Article

Drug-induced liver injury can lead to changes of the biliary tree that resemble sclerosing cholangitis. These changes can be seen on magnetic resonance cholangiopancreatography. Idiosyncratic drug-induced liver injury (DILI) has a variable presentation including cholestatic liver injury,1 in which case magnetic resonance imaging (MRI) is often performed to exclude pancreaticobiliary causes of obstruction. Sclerosing cholangitis (SC)-like changes on imaging have been described anecdotally with DILI.2,3 A recent study of 25 consecutive, unselected DILI patients found that 10% had SC-like changes on magnetic resonance cholangiopancreatography (MRCP).4 The aim of the current study was to identify the clinical features of patients enrolled in the U.S. Drug Induced Liver Injury Network (DILIN) prospective study who had SC-like changes on MRCP.

Full Text

Duke Authors

Cited Authors

  • Ahmad, J; Rossi, S; Rodgers, SK; Ghabril, M; Fontana, RJ; Stolz, A; Hayashi, PH; Barnhart, H; Kleiner, DE; Bjornsson, ES

Published Date

  • March 2019

Published In

Volume / Issue

  • 17 / 4

Start / End Page

  • 789 - 790

PubMed ID

  • 29966706

Pubmed Central ID

  • 29966706

Electronic International Standard Serial Number (EISSN)

  • 1542-7714

International Standard Serial Number (ISSN)

  • 1542-3565

Digital Object Identifier (DOI)

  • 10.1016/j.cgh.2018.06.035


  • eng