External validation of the adult spinal deformity (ASD) frailty index (ASD-FI)


Journal Article

© 2018, Springer-Verlag GmbH Germany, part of Springer Nature. Purpose: To assess the ability of the recently developed adult spinal deformity frailty index (ASD-FI) to predict odds of perioperative complications, odds of reoperation, and length of hospital stay after adult spinal deformity (ASD) surgery using a database other than the one used to create the index. Methods: We used the ASD-FI to calculate frailty scores for 266 ASD patients who had minimum postoperative follow-up of 2 years in the European Spine Study Group (ESSG) database. Patients were enrolled from 2012 through 2013. Using ASD-FI scores, we categorized patients as not frail (NF) (< 0.3 points), frail (0.3–0.5 points), or severely frail (SF) (> 0.5 points). Multivariable logistic regression, adjusted for preoperative and surgical factors such as operative time and blood loss, was performed to determine the relationship between ASD-FI category and odds of major complications, odds of reoperation, and length of hospital stay. Results: We categorized 135 patients (51%) as NF, 90 patients (34%) as frail, and 41 patients (15%) as SF. Overall mean ASD-FI score was 0.29 (range 0–0.8). The adjusted odds of experiencing a major intraoperative or postoperative complication (OR 4.5, 95% CI 2.0–10) or having a reoperation (OR 3.9, 95% CI 1.7–8.9) were higher for SF patients compared with NF patients. Mean hospital stay was 2.1 times longer (95% CI 1.8–2.4) for SF patients compared with NF patients. Conclusions: Greater patient frailty, as measured by the ASD-FI, is associated with longer hospital stays and greater odds of major complications and reoperation. Graphical abstract: These slides can be retrieved under Electronic Supplementary Material.[Figure not available: see fulltext.].

Full Text

Duke Authors

Cited Authors

  • Miller, EK; Vila-Casademunt, A; Neuman, BJ; Sciubba, DM; Kebaish, KM; Smith, JS; Alanay, A; Acaroglu, ER; Kleinstück, F; Obeid, I; Sánchez Pérez-Grueso, FJ; Carreon, LY; Schwab, FJ; Bess, S; Scheer, JK; Lafage, V; Shaffrey, CI; Pellisé, F; Ames, CP

Published Date

  • September 1, 2018

Published In

Volume / Issue

  • 27 / 9

Start / End Page

  • 2331 - 2338

Electronic International Standard Serial Number (EISSN)

  • 1432-0932

International Standard Serial Number (ISSN)

  • 0940-6719

Digital Object Identifier (DOI)

  • 10.1007/s00586-018-5575-3

Citation Source

  • Scopus