A cost analysis of bone morphogenetic protein versus autogenous iliac crest bone graft in single-level anterior lumbar fusion.

Journal Article (Journal Article)

An economic model was developed to compare costs of stand-alone anterior lumbar interbody fusion with recombinant human bone morphogenetic protein 2 on an absorbable collagen sponge versus autogenous iliac crest bone graft in a tapered cylindrical cage or a threaded cortical bone dowel. The economic model was developed from clinical trial data, peer-reviewed literature, and clinical expert opinion. The upfront price of bone morphogenetic protein (3380 dollars) is likely to be offset to a significant extent by reductions in the use of other medical resources, particularly if costs incurred during the 2 year period following the index hospitalization are taken into account.

Full Text

Duke Authors

Cited Authors

  • Polly, DW; Ackerman, SJ; Shaffrey, CI; Ogilvie, JW; Wang, JC; Stralka, SW; Mafilios, MS; Heim, SE; Sandhu, HS

Published Date

  • October 1, 2003

Published In

Volume / Issue

  • 26 / 10

Start / End Page

  • 1027 - 1037

PubMed ID

  • 14577525

International Standard Serial Number (ISSN)

  • 0147-7447

Digital Object Identifier (DOI)

  • 10.3928/0147-7447-20031001-12


  • eng

Conference Location

  • United States