Sexual dysfunction and reproductive concerns in young women with breast cancer: Type, prevalence, and predictors of problems.

Published

Journal Article

OBJECTIVE: A dearth of studies focusing on young women (<40 years) with breast cancer have hampered the understanding of the type, prevalence, and predictors of sexual dysfunction and reproductive concerns in this population. METHODS: Data were collected from 181 women (response rate = 60%) diagnosed with breast cancer approximately 2 years previously (age 21-39) using the Swedish National Quality Registry for Breast Cancer and a survey including standardized measures of sexual dysfunction, reproductive concerns, body image, and health-related quality of life. Multivariable logistic binary regression analyses were used to identify predictors of sexual dysfunction and reproductive concerns. RESULTS: Sexual dysfunction in at least one domain was reported by 68% of the women, and a high level of reproductive concerns in at least one dimension was reported by 58%. Model results showed that current endocrine treatment was a significant predictor of dysfunction related to lubrication (OR 3.8, 95% CI 1.2-12.1) and vaginal discomfort (OR 8.7, 95% CI 1.5-51.5). Negative body image was related to satisfaction with sex life (OR 1.1, 95% CI 1.0-1.2). A high level of reproductive concerns was predicted by a wish for (additional) children in the future (OR 3.4, 95% CI 1.1-10.2) and by previous chemotherapy (OR 2.5, 95% CI 1.1-5.9). CONCLUSIONS: Sexual dysfunction and reproductive concerns are common in young women with breast cancer. Current endocrine treatment, previous chemotherapy, a negative body image, and a wish for children in the future predict higher level of problems.

Full Text

Duke Authors

Cited Authors

  • Ljungman, L; Ahlgren, J; Petersson, L-M; Flynn, KE; Weinfurt, K; Gorman, JR; Wettergren, L; Lampic, C

Published Date

  • December 2018

Published In

Volume / Issue

  • 27 / 12

Start / End Page

  • 2770 - 2777

PubMed ID

  • 30203884

Pubmed Central ID

  • 30203884

Electronic International Standard Serial Number (EISSN)

  • 1099-1611

Digital Object Identifier (DOI)

  • 10.1002/pon.4886

Language

  • eng

Conference Location

  • England