Standard-dose and short-term corticosteroid therapy in immunoglobulin-resistant Kawasaki disease.


Journal Article

Six patients with Kawasaki disease (KD) were treated with prednisolone (1 to 2 mg/kg/day) for 3 days (from days 10 to 12 after the onset of the illness) after apparently unsuccessful treatment with intravenous immunoglobulin (IVIG, 2 g/kg/dose and additional 1 g/kg/dose). Five patients responded immediately to the first course of prednisolone infusion. One patient failed to respond to the first course of prednisolone therapy, but he did respond to the second 3-day course of therapy. None of the patients demonstrated a further progression of coronary artery dilatation or any adverse effects. Standard-dose and short-term corticosteroid therapy therefore appears to be a safe and effective treatment for patients with IVIG-resistant KD.

Full Text

Cited Authors

  • Takeshita, S; Kawamura, Y; Nakatani, K; Tsujimoto, H; Tokutomi, T

Published Date

  • June 2005

Published In

Volume / Issue

  • 44 / 5

Start / End Page

  • 423 - 426

PubMed ID

  • 15965549

Pubmed Central ID

  • 15965549

Electronic International Standard Serial Number (EISSN)

  • 1938-2707

International Standard Serial Number (ISSN)

  • 0009-9228

Digital Object Identifier (DOI)

  • 10.1177/000992280504400507


  • eng