Application of SNPs in forensic casework: identification of pathological and autoptical specimens due to sample mix-up.

Published

Journal Article

The analysis of single nucleotide polymorphisms (SNPs) together with conventional short tandem repeat (STR) and mitochondrial DNA (mtDNA) typing provide a forensic genetic approach for the identification of pathological and autoptical specimens in cases where the average length of DNA fragments is shorter than 150 bp in highly degraded samples. We applied a forensic genetic approach to digesta accidentally left after a training autopsy. PCR products were not amplified from samples containing the STR loci or common sequences used for mtDNA typing. The application of SNPs and deletion polymorphisms provides an alternative approach for DNA typing analysis.

Full Text

Cited Authors

  • Takada, Y; Tokutomi, T; Kanetake, J; Mukaida, M

Published Date

  • April 2009

Published In

Volume / Issue

  • 11 Suppl 1 /

Start / End Page

  • S196 - S197

PubMed ID

  • 19289302

Pubmed Central ID

  • 19289302

Electronic International Standard Serial Number (EISSN)

  • 1873-4162

International Standard Serial Number (ISSN)

  • 1344-6223

Digital Object Identifier (DOI)

  • 10.1016/j.legalmed.2009.02.006

Language

  • eng