Right Ventricular Function in Left Heart Disease.

Journal Article (Journal Article;Review)

Right ventricular (RV) function is an independent prognostic factor for short- and long-term outcomes in cardiac surgical patients. Patients with mitral valve (MV) disease are at increased risk of RV dysfunction before and after MV operations. Yet RV function is not part of criteria for decision making or risk stratification in this setting. The role of MV disease in the development of pulmonary hypertension (PHTN) and the ultimate impact of PHTN on RV function have been well described. Nonetheless, there are other mechanisms by which MV disease and MV surgery affect RV performance. Research suggests that PHTN may not be the most important determinant of RV dysfunction. Both RV dysfunction and PHTN have independent prognostic significance. This review explores the unique anatomic and functional features of the RV and the pathophysiologic and prognostic implications of RV dysfunction in patients with MV disease in the perioperative period.

Full Text

Duke Authors

Cited Authors

  • Del Rio, JM; Grecu, L; Nicoara, A

Published Date

  • March 2019

Published In

Volume / Issue

  • 23 / 1

Start / End Page

  • 88 - 107

PubMed ID

  • 30229690

Electronic International Standard Serial Number (EISSN)

  • 1940-5596

Digital Object Identifier (DOI)

  • 10.1177/1089253218799345


  • eng

Conference Location

  • United States