Peripheral blood stem cell transplantation in breast cancer.

Journal Article (Journal Article;Review)

Over the past decade, peripheral blood progenitor cells (PBPCs) have replaced bone marrow as the major source of haematopoietic support. This transition from marrow to PBPCs is due to the fact that, for many clinical studies, a significantly faster rate of engraftment, particularly for platelets, has been demonstrated for patients who receive PBPC support when compared to similarly treated patients who are transplanted with bone marrow. The leukapheresis procedure itself, quality of PBPC graft, methods of PBPC mobilization, purging, and ex vivo expansion will be discussed in detail.

Full Text

Duke Authors

Cited Authors

  • Shpall, EJ; Jones, RB; Bearman, SI; Cagnoni, PJ; Nieto, Y; McNiece, IK

Published Date

  • March 1999

Published In

  • Baillieres Best Pract Res Clin Haematol

Volume / Issue

  • 12 / 1-2

Start / End Page

  • 219 - 232

PubMed ID

  • 11000995

Digital Object Identifier (DOI)

  • 10.1053/beha.1999.0019


  • eng

Conference Location

  • England