Pancreatic Cancer Chemoprevention Translational Workshop: Meeting Report.


Conference Paper

Pancreatic cancer is the fourth leading cause of cancer related deaths in the United States with a 5-year survival rate of less than 10%. The Division of Cancer Prevention of the National Cancer Institute sponsored the Pancreatic Cancer Chemoprevention Translational Workshop on September 10 to 11, 2015. The goal of the workshop was to obtain information regarding the current state of the science and future scientific areas that should be prioritized for pancreatic cancer prevention research, including early detection and intervention for high-risk precancerous lesions. The workshop addressed the molecular/genetic landscape of pancreatic cancer and precursor lesions, high-risk populations and criteria to identify a high-risk population for potential chemoprevention trials, identification of chemopreventative/immunopreventative agents, and use of potential biomarkers and imaging for assessing short-term efficacy of a preventative agent. The field of chemoprevention for pancreatic cancer is emerging, and this workshop was organized to begin to address these important issues and promote multi-institutional efforts in this area. The meeting participants recommended the development of an National Cancer Institute working group to coordinate efforts, provide a framework, and identify opportunities for chemoprevention of pancreatic cancer.

Full Text

Duke Authors

Cited Authors

  • Miller, MS; Allen, P; Brentnall, TA; Goggins, M; Hruban, RH; Petersen, GM; Rao, CV; Whitcomb, DC; Brand, RE; Chari, ST; Klein, AP; Lubman, DM; Rhim, AD; Simeone, DM; Wolpin, BM; Umar, A; Srivastava, S; Steele, VE; Rinaudo, JAS

Published Date

  • September 2016

Published In

Volume / Issue

  • 45 / 8

Start / End Page

  • 1080 - 1091

PubMed ID

  • 27518363

Pubmed Central ID

  • 27518363

Electronic International Standard Serial Number (EISSN)

  • 1536-4828

Digital Object Identifier (DOI)

  • 10.1097/MPA.0000000000000705

Conference Location

  • United States