Simultaneous resection for rectal cancer with synchronous liver metastasis is a safe procedure.


Journal Article

BACKGROUND: One quarter of colorectal cancer patients will present with liver metastasis at the time of diagnosis. Recent studies have shown that simultaneous resections are safe and feasible for stage IV colon cancer. Limited data are available for simultaneous surgery in stage IV rectal cancer patients. METHODS: One hundred ninety-eight patients underwent surgical treatment for stage IV rectal cancer. In 145 (73%) patients, a simultaneous procedure was performed. Fifty-three (27%) patients underwent staged liver resection. A subpopulation of 69 (35%) patients underwent major liver resection (3 segments or more) and 30 (44%) patients with simultaneous surgery. RESULTS: The demographics of the 2 groups were similar. Complication rates were comparable for simultaneous or staged resections, even in the group subjected to major liver resection. Total hospital stay was significantly shorter for the simultaneously resected patients (P < .01). CONCLUSIONS: Simultaneous resection of rectal primaries and liver metastases is a safe procedure in carefully selected patients at high-volume institutions, even if major liver resections are required.

Full Text

Duke Authors

Cited Authors

  • Silberhumer, GR; Paty, PB; Temple, LK; Araujo, RLC; Denton, B; Gonen, M; Nash, GM; Allen, PJ; DeMatteo, RP; Guillem, J; Weiser, MR; D'Angelica, MI; Jarnagin, WR; Wong, DW; Fong, Y

Published Date

  • June 2015

Published In

Volume / Issue

  • 209 / 6

Start / End Page

  • 935 - 942

PubMed ID

  • 25601556

Pubmed Central ID

  • 25601556

Electronic International Standard Serial Number (EISSN)

  • 1879-1883

Digital Object Identifier (DOI)

  • 10.1016/j.amjsurg.2014.09.024


  • eng

Conference Location

  • United States