Desmoid tumors of the chest wall.

Journal Article (Journal Article)

Desmoid tumors are rare soft tissue neoplasms derived from fascial or musculoaponeurotic structures. These tumors are histologically benign but may behave aggressively at the local level with multiple recurrences after complete resection being common. Chest wall desmoids account for approximately 20% of all patients with desmoid tumors. Patients with these lesions are often asymptomatic and thus commonly present with lesions greater than 10 cm in size. The treatment for these neoplasms remains margin negative surgical excision, and, given the often large size at presentation, may require extensive chest wall resection. When this is required, chest wall reconstruction with either prosthetic material and/or autologous tissue may be performed. There may be recurrence in as many as 75% of patients. Neither adjuvant radiotherapy or chemotherapy have been shown to reduce the rate of recurrence. Recurrence should also be treated with surgical resection because patients who undergo complete surgical resection of recurrence are as likely to remain disease free after resection as patients who present with primary disease.

Full Text

Duke Authors

Cited Authors

  • Allen, PJ; Shriver, CD

Published Date

  • July 1999

Published In

Volume / Issue

  • 11 / 3

Start / End Page

  • 264 - 269

PubMed ID

  • 10451258

International Standard Serial Number (ISSN)

  • 1043-0679

Digital Object Identifier (DOI)

  • 10.1016/s1043-0679(99)70067-5


  • eng

Conference Location

  • United States