Recurrence patterns of intraductal papillary mucinous neoplasms of the pancreas on enhanced computed tomography.

Published

Journal Article

OBJECTIVE: To characterize imaging features and findings in recurrent intraductal papillary mucinous neoplasms (IPMN); thereby reconciling the "field defect" theory with the appearance of recurrences distant from the resection margin. METHODS: Computed tomography findings were reviewed in 89 patients who were resected with IPMN. At follow-up, the appearance of the pancreatic duct, features of recurrent masses, evidence of enhancement, calcifications, lymphadenopathy, and metastases were recorded. RESULTS: Fourteen (16%) of the 89 patients had evidence of recurrence. Nine (64%) of the 14 patients demonstrated evidence for local recurrence. Ten recurrent lesions were noted in 9 patients. Patients with recurrence demonstrated an increase of pancreatic ductal dilatation of 3.3 mm, whereas patients without recurrence either had no dilatation or dilatation which then decreased over time. CONCLUSIONS: Computed tomography findings suspicious for tumor recurrence include enlarging mass (either solid, cystic or both), progressive ductal dilatation, or extrapancreatic disease. There was a lack of correlation between margin status and location of recurrence within the pancreas consistent with the global field defect theory of IPMN.

Full Text

Duke Authors

Cited Authors

  • Landa, J; Allen, P; D'Angelica, M; Schwartz, LH

Published Date

  • November 2009

Published In

Volume / Issue

  • 33 / 6

Start / End Page

  • 838 - 843

PubMed ID

  • 19940647

Pubmed Central ID

  • 19940647

Electronic International Standard Serial Number (EISSN)

  • 1532-3145

International Standard Serial Number (ISSN)

  • 0363-8715

Digital Object Identifier (DOI)

  • 10.1097/rct.0b013e3181a7e2a8

Language

  • eng