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Laparoscopic versus open liver resection: a matched-pair case control study.

Publication ,  Journal Article
Ito, K; Ito, H; Are, C; Allen, PJ; Fong, Y; DeMatteo, RP; Jarnagin, WR; D'Angelica, MI
Published in: J Gastrointest Surg
December 2009

BACKGROUND: Laparoscopic liver resection (LLR) has become an increasingly popular operation; however, its theoretical benefits remain unproven. The aim of this study was to conduct a comparative outcome study between LLR and matched-pair open liver resections (OLR). METHODS: Sixty five patients underwent attempted LLR from 1998 through 2008; 52 of which were completed laparoscopically. Patients who underwent OLR prior to 1998 were matched to laparoscopic cases for demographics, comorbidities, diagnosis, tumor characteristics, procedure, and background liver. Perioperative and oncologic outcomes were compared between the two groups. Analyses were performed excluding and including conversion cases. RESULTS: Characteristics were comparable between both groups. LLR was associated with significant reductions in estimated blood loss, frequency of transfusion, frequency of Pringle maneuver, postoperative morbidity, time to recovery, length of hospital stay, and incidence of incisional hernia. For patients with malignant tumors, there were no positive surgical margins or local recurrence in either group and the overall pattern of recurrence was similar. CONCLUSION: For well-selected patients, LLR is a feasible operation that does not compromise operative or oncologic outcomes. While LLR was associated with some benefits, these can only be definitively proven in a randomized controlled trial.

Duke Scholars

Published In

J Gastrointest Surg

DOI

EISSN

1873-4626

Publication Date

December 2009

Volume

13

Issue

12

Start / End Page

2276 / 2283

Location

Netherlands

Related Subject Headings

  • Treatment Outcome
  • Surgery
  • Middle Aged
  • Male
  • Liver Neoplasms
  • Laparoscopy
  • Humans
  • Hepatectomy
  • Female
  • Case-Control Studies
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ito, K., Ito, H., Are, C., Allen, P. J., Fong, Y., DeMatteo, R. P., … D’Angelica, M. I. (2009). Laparoscopic versus open liver resection: a matched-pair case control study. J Gastrointest Surg, 13(12), 2276–2283. https://doi.org/10.1007/s11605-009-0993-5
Ito, Kaori, Hiromichi Ito, Chandrakanth Are, Peter J. Allen, Yuman Fong, Ronald P. DeMatteo, William R. Jarnagin, and Michael I. D’Angelica. “Laparoscopic versus open liver resection: a matched-pair case control study.J Gastrointest Surg 13, no. 12 (December 2009): 2276–83. https://doi.org/10.1007/s11605-009-0993-5.
Ito K, Ito H, Are C, Allen PJ, Fong Y, DeMatteo RP, et al. Laparoscopic versus open liver resection: a matched-pair case control study. J Gastrointest Surg. 2009 Dec;13(12):2276–83.
Ito, Kaori, et al. “Laparoscopic versus open liver resection: a matched-pair case control study.J Gastrointest Surg, vol. 13, no. 12, Dec. 2009, pp. 2276–83. Pubmed, doi:10.1007/s11605-009-0993-5.
Ito K, Ito H, Are C, Allen PJ, Fong Y, DeMatteo RP, Jarnagin WR, D’Angelica MI. Laparoscopic versus open liver resection: a matched-pair case control study. J Gastrointest Surg. 2009 Dec;13(12):2276–2283.
Journal cover image

Published In

J Gastrointest Surg

DOI

EISSN

1873-4626

Publication Date

December 2009

Volume

13

Issue

12

Start / End Page

2276 / 2283

Location

Netherlands

Related Subject Headings

  • Treatment Outcome
  • Surgery
  • Middle Aged
  • Male
  • Liver Neoplasms
  • Laparoscopy
  • Humans
  • Hepatectomy
  • Female
  • Case-Control Studies