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Resolution of hepatic encephalopathy following hepatic artery embolization in a patient with well-differentiated neuroendocrine tumor metastatic to the liver.

Publication ,  Journal Article
Erinjeri, JP; Deodhar, A; Thornton, RH; Allen, PJ; Getrajdman, GI; Brown, KT; Sofocleous, CT; Reidy, DL
Published in: Cardiovasc Intervent Radiol
June 2010

Hepatic encephalopathy is considered a contraindication to hepatic artery embolization. We describe a patient with a well-differentiated neuroendocrine tumor metastatic to the liver with refractory hepatic encephalopathy and normal liver function tests. The encephalopathy was refractory to standard medical therapy with lactulose. The patient's mental status returned to baseline after three hepatic artery embolization procedures. Arteriography and ultrasound imaging before and after embolization suggest that the encephalopathy was due to arterioportal shunting causing hepatofugal portal venous flow and portosystemic shunting. In patients with a primary or metastatic well-differentiated neuroendocrine tumor whose refractory hepatic encephalopathy is due to portosystemic shunting (rather than global hepatic dysfunction secondary to tumor burden), hepatic artery embolization can be performed safely and effectively.

Duke Scholars

Published In

Cardiovasc Intervent Radiol

DOI

EISSN

1432-086X

Publication Date

June 2010

Volume

33

Issue

3

Start / End Page

610 / 614

Location

United States

Related Subject Headings

  • Ultrasonography
  • Tomography, X-Ray Computed
  • Nuclear Medicine & Medical Imaging
  • Neuroendocrine Tumors
  • Middle Aged
  • Male
  • Liver Neoplasms
  • Liver Function Tests
  • Humans
  • Hepatic Encephalopathy
 

Citation

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MLA
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Erinjeri, J. P., Deodhar, A., Thornton, R. H., Allen, P. J., Getrajdman, G. I., Brown, K. T., … Reidy, D. L. (2010). Resolution of hepatic encephalopathy following hepatic artery embolization in a patient with well-differentiated neuroendocrine tumor metastatic to the liver. Cardiovasc Intervent Radiol, 33(3), 610–614. https://doi.org/10.1007/s00270-009-9698-0
Erinjeri, Joseph P., Ajita Deodhar, Raymond H. Thornton, Peter J. Allen, George I. Getrajdman, Karen T. Brown, Constantinos T. Sofocleous, and Diane L. Reidy. “Resolution of hepatic encephalopathy following hepatic artery embolization in a patient with well-differentiated neuroendocrine tumor metastatic to the liver.Cardiovasc Intervent Radiol 33, no. 3 (June 2010): 610–14. https://doi.org/10.1007/s00270-009-9698-0.
Erinjeri JP, Deodhar A, Thornton RH, Allen PJ, Getrajdman GI, Brown KT, et al. Resolution of hepatic encephalopathy following hepatic artery embolization in a patient with well-differentiated neuroendocrine tumor metastatic to the liver. Cardiovasc Intervent Radiol. 2010 Jun;33(3):610–4.
Erinjeri, Joseph P., et al. “Resolution of hepatic encephalopathy following hepatic artery embolization in a patient with well-differentiated neuroendocrine tumor metastatic to the liver.Cardiovasc Intervent Radiol, vol. 33, no. 3, June 2010, pp. 610–14. Pubmed, doi:10.1007/s00270-009-9698-0.
Erinjeri JP, Deodhar A, Thornton RH, Allen PJ, Getrajdman GI, Brown KT, Sofocleous CT, Reidy DL. Resolution of hepatic encephalopathy following hepatic artery embolization in a patient with well-differentiated neuroendocrine tumor metastatic to the liver. Cardiovasc Intervent Radiol. 2010 Jun;33(3):610–614.
Journal cover image

Published In

Cardiovasc Intervent Radiol

DOI

EISSN

1432-086X

Publication Date

June 2010

Volume

33

Issue

3

Start / End Page

610 / 614

Location

United States

Related Subject Headings

  • Ultrasonography
  • Tomography, X-Ray Computed
  • Nuclear Medicine & Medical Imaging
  • Neuroendocrine Tumors
  • Middle Aged
  • Male
  • Liver Neoplasms
  • Liver Function Tests
  • Humans
  • Hepatic Encephalopathy