Natural history of patients with subcentimeter pulmonary nodules undergoing hepatic resection for metastatic colorectal cancer.
BACKGROUND: CT imaging frequently detects subcentimeter pulmonary nodules (SPN) in patients undergoing resection of colorectal cancer liver metastases. Their clinical significance is unknown. STUDY DESIGN: Patients were identified who underwent hepatic resection for colorectal cancer liver metastases between October 2004 and March 2006. The presence and imaging features of preoperative SPN were analyzed for their association with progression-free survival (PFS), disease-specific survival (DSS), and SPN progression. RESULTS: One hundred sixty patients underwent liver resection and 68 (43%) had SPN identified preoperatively. Median number of nodules was 1 (75(th) percentile:
Maithel, SK; Ginsberg, MS; D'Amico, F; DeMatteo, RP; Allen, PJ; Fong, Y; Blumgart, LH; Jarnagin, WR; D'Angelica, MI
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