Medical and surgical treatment of chronic venous ulcers.


Journal Article (Review)

Venous ulcer of the lower extremity is a common vascular condition and is associated with decreased quality of life, reduced mobility, and social isolation. Treatment of chronic venous ulcer (CVU) includes compression therapy, debridement of the ulcer when necessary, and wound care. Collagen and antimicrobial dressings can improve the proportion of ulcers healed compared with compression alone. Acellular skin equivalents are not superior to compression, but cellular human skin equivalents can promote more rapid healing, particularly in patients with longstanding ulcers. Current vascular surgical practice is to eliminate documented reflux or obstruction in patients with CVU that have failed a 3-month period of compression dressing, debridement, and local wound care. We found that surgical treatment of the superficial venous system can decrease the time to healing of CVUs compared with compression therapy alone, but does not increase the proportion of ulcers healed.

Full Text

Duke Authors

Cited Authors

  • Cooper, MA; Qazi, U; Bass, E; Zenilman, J; Lazarus, G; Valle, MF; Malas, MB

Published Date

  • September 2015

Published In

Volume / Issue

  • 28 / 3-4

Start / End Page

  • 160 - 164

PubMed ID

  • 27113282

Pubmed Central ID

  • 27113282

Electronic International Standard Serial Number (EISSN)

  • 1558-4518

International Standard Serial Number (ISSN)

  • 0895-7967

Digital Object Identifier (DOI)

  • 10.1053/j.semvascsurg.2015.12.003


  • eng