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Combat Wound Initiative program.

Publication ,  Journal Article
Stojadinovic, A; Elster, E; Potter, BK; Davis, TA; Tadaki, DK; Brown, TS; Ahlers, S; Attinger, CE; Andersen, RC; Burris, D; Centeno, J ...
Published in: Mil Med
July 2010

The Combat Wound Initiative (CWI) program is a collaborative, multidisciplinary, and interservice public-private partnership that provides personalized, state-of-the-art, and complex wound care via targeted clinical and translational research. The CWI uses a bench-to-bedside approach to translational research, including the rapid development of a human extracorporeal shock wave therapy (ESWT) study in complex wounds after establishing the potential efficacy, biologic mechanisms, and safety of this treatment modality in a murine model. Additional clinical trials include the prospective use of clinical data, serum and wound biomarkers, and wound gene expression profiles to predict wound healing/failure and additional clinical patient outcomes following combat-related trauma. These clinical research data are analyzed using machine-based learning algorithms to develop predictive treatment models to guide clinical decision-making. Future CWI directions include additional clinical trials and study centers and the refinement and deployment of our genetically driven, personalized medicine initiative to provide patient-specific care across multiple medical disciplines, with an emphasis on combat casualty care.

Duke Scholars

Published In

Mil Med

DOI

ISSN

0026-4075

Publication Date

July 2010

Volume

175

Issue

7 Suppl

Start / End Page

18 / 24

Location

England

Related Subject Headings

  • Wounds and Injuries
  • Wound Healing
  • Warfare
  • United States
  • Translational Research, Biomedical
  • Strategic, Defence & Security Studies
  • Public-Private Sector Partnerships
  • Neovascularization, Physiologic
  • Military Personnel
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
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Stojadinovic, A., Elster, E., Potter, B. K., Davis, T. A., Tadaki, D. K., Brown, T. S., … Zenilman, J. M. (2010). Combat Wound Initiative program. Mil Med, 175(7 Suppl), 18–24. https://doi.org/10.7205/milmed-d-10-00156
Stojadinovic, Alexander, Eric Elster, Benjamin K. Potter, Thomas A. Davis, Doug K. Tadaki, Trevor S. Brown, Stephen Ahlers, et al. “Combat Wound Initiative program.Mil Med 175, no. 7 Suppl (July 2010): 18–24. https://doi.org/10.7205/milmed-d-10-00156.
Stojadinovic A, Elster E, Potter BK, Davis TA, Tadaki DK, Brown TS, et al. Combat Wound Initiative program. Mil Med. 2010 Jul;175(7 Suppl):18–24.
Stojadinovic, Alexander, et al. “Combat Wound Initiative program.Mil Med, vol. 175, no. 7 Suppl, July 2010, pp. 18–24. Pubmed, doi:10.7205/milmed-d-10-00156.
Stojadinovic A, Elster E, Potter BK, Davis TA, Tadaki DK, Brown TS, Ahlers S, Attinger CE, Andersen RC, Burris D, Centeno J, Champion H, Crumbley DR, Denobile J, Duga M, Dunne JR, Eberhardt J, Ennis WJ, Forsberg JA, Hawksworth J, Helling TS, Lazarus GS, Milner SM, Mullick FG, Owner CR, Pasquina PF, Patel CR, Peoples GE, Nissan A, Ring M, Sandberg GD, Schaden W, Schultz GS, Scofield T, Shawen SB, Sheppard FR, Stannard JP, Weina PJ, Zenilman JM. Combat Wound Initiative program. Mil Med. 2010 Jul;175(7 Suppl):18–24.

Published In

Mil Med

DOI

ISSN

0026-4075

Publication Date

July 2010

Volume

175

Issue

7 Suppl

Start / End Page

18 / 24

Location

England

Related Subject Headings

  • Wounds and Injuries
  • Wound Healing
  • Warfare
  • United States
  • Translational Research, Biomedical
  • Strategic, Defence & Security Studies
  • Public-Private Sector Partnerships
  • Neovascularization, Physiologic
  • Military Personnel
  • Humans