Present status of pyoderma gangrenosum. Review of 21 cases.

Journal Article (Journal Article;Review)

This article summarizes the management of 22 cases of pyoderma gangrenosum over the past four years at the hospital of the University of Pennsylvania, Philadelphia. Eighteen patients with pyoderma gangrenosum were studied using the most sensitive routine laboratory method for detection of monoclonal immunoglobulins, immunofixation electrophoresis. Four cases of IgA gammopathy were detected, confirming previous reports of the incidence of monoclonal gammopathy in pyoderma gangrenosum. High-dose glucocorticoid therapy (pulse therapy) is an effective treatment for some severe, refractory cases of pyoderma gangrenosum. Eight patients were treated with pulse therapy. Six responded favorably, and none had serious complications.

Full Text

Duke Authors

Cited Authors

  • Prystowsky, JH; Kahn, SN; Lazarus, GS

Published Date

  • January 1989

Published In

Volume / Issue

  • 125 / 1

Start / End Page

  • 57 - 64

PubMed ID

  • 2642682

International Standard Serial Number (ISSN)

  • 0003-987X


  • eng

Conference Location

  • United States