Evaluating the Use of Silicone Wristbands To Measure Personal Exposure to Brominated Flame Retardants.

Published

Journal Article

Biomarkers remain the gold standard for assessing chemical exposure. However, silicone wristbands may provide some added benefits for characterizing personal exposures compared to single biomarker measurements, such as decreased costs, noninvasive sampling, and increased ease of analysis. Previously, we validated their use in characterizing exposure to organophosphate flame retardants (PFRs). However, it is unclear whether these results would extend to chemicals like polybrominated diphenyl ethers (PBDEs), which biomagnify and have longer half-lives than PFRs in the body. This study sought to determine if accumulation of PBDEs on wristbands was correlated to serum biomarkers. Adult participants ( n = 30) provided serum samples and wore wristbands for 7 days. PBDEs and 6 novel brominated flame retardants (BFRs) were measured on wristbands, and serum samples were analyzed for PBDE biomarkers. Like most PBDE congeners, 5 of 6 novel BFRs were frequently detected on wristbands (≥90% of bands). In particular, decabromodiphenyl ethane (DBDPE) was detected in all wristbands in this study and was significantly correlated with BDE-209, suggesting a similar source and exposure pathway. Wristband levels of BDE-47, -99, -100, and -153 were significantly and positively associated with respective serum biomarkers ( rs = 0.39-0.57, p < 0.05). This study demonstrates that silicone wristbands can accurately detect personal PBDE exposures.

Full Text

Duke Authors

Cited Authors

  • Hammel, SC; Phillips, AL; Hoffman, K; Stapleton, HM

Published Date

  • October 2, 2018

Published In

Volume / Issue

  • 52 / 20

Start / End Page

  • 11875 - 11885

PubMed ID

  • 30216050

Pubmed Central ID

  • 30216050

Electronic International Standard Serial Number (EISSN)

  • 1520-5851

International Standard Serial Number (ISSN)

  • 0013-936X

Digital Object Identifier (DOI)

  • 10.1021/acs.est.8b03755

Language

  • eng