A systematic review of evidence that enteroviruses may be zoonotic.

Journal Article (Journal Article;Systematic Review)

Enteroviruses infect millions of humans annually worldwide, primarily infants and children. With a high mutation rate and frequent recombination, enteroviruses are noted to evolve and change over time. Given the evidence that human enteroviruses are commonly found in other mammalian species and that some human and animal enteroviruses are genetically similar, it is possible that enzootic enteroviruses may also be infecting human populations. We conducted a systematic review of the English and Chinese literature published between 2007 and 2017 to examine evidence that enteroviruses may be zoonotic. Of the 2704 articles screened for inclusion, 16 articles were included in the final review. The review of these articles yielded considerable molecular evidence of zooanthroponosis transmission, particularly among non-human primates. While there were more limited instances of anthropozoonosis transmission, the available data support the biological plausibility of cross-species transmission and the need to conduct periodic surveillance at the human-animal interface.

Full Text

Duke Authors

Cited Authors

  • Fieldhouse, JK; Wang, X; Mallinson, KA; Tsao, RW; Gray, GC

Published Date

  • September 26, 2018

Published In

Volume / Issue

  • 7 / 1

Start / End Page

  • 164 -

PubMed ID

  • 30258048

Pubmed Central ID

  • PMC6158190

Electronic International Standard Serial Number (EISSN)

  • 2222-1751

Digital Object Identifier (DOI)

  • 10.1038/s41426-018-0159-1

Language

  • eng

Conference Location

  • United States