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Handheld Adaptive Optics Scanning Laser Ophthalmoscope.

Publication ,  Journal Article
DuBose, T; Nankivil, D; LaRocca, F; Waterman, G; Hagan, K; Polans, J; Keller, B; Tran-Viet, D; Vajzovic, L; Kuo, AN; Toth, CA; Izatt, JA; Farsiu, S
Published in: Optica
September 20, 2018

Adaptive optics scanning laser ophthalmoscopy (AOSLO) has enabled in vivo visualization and enhanced understanding of retinal structure and function. Current generation AOSLOs have a large footprint and are mainly limited to imaging cooperative adult subjects. To extend the application of AOSLO to new patient populations, we have designed the first portable handheld AOSLO (HAOSLO) system. By incorporating a novel computational wavefront sensorless AO algorithm and custom optics, we have miniaturized our HAOSLO to weigh less than 200 grams. HAOSLO imaged the cones closest to the fovea with a handheld probe in adults and captured the first AO-enhanced image of cones in infants.

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Published In

Optica

DOI

ISSN

2334-2536

Publication Date

September 20, 2018

Volume

5

Issue

9

Start / End Page

1027 / 1036

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 1005 Communications Technologies
  • 0906 Electrical and Electronic Engineering
  • 0205 Optical Physics
 

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DuBose, T., Nankivil, D., LaRocca, F., Waterman, G., Hagan, K., Polans, J., … Farsiu, S. (2018). Handheld Adaptive Optics Scanning Laser Ophthalmoscope. Optica, 5(9), 1027–1036. https://doi.org/10.1364/OPTICA.5.001027
DuBose, Theodore, Derek Nankivil, Francesco LaRocca, Gar Waterman, Kristen Hagan, James Polans, Brenton Keller, et al. “Handheld Adaptive Optics Scanning Laser Ophthalmoscope.Optica 5, no. 9 (September 20, 2018): 1027–36. https://doi.org/10.1364/OPTICA.5.001027.
DuBose T, Nankivil D, LaRocca F, Waterman G, Hagan K, Polans J, et al. Handheld Adaptive Optics Scanning Laser Ophthalmoscope. Optica. 2018 Sep 20;5(9):1027–36.
DuBose, Theodore, et al. “Handheld Adaptive Optics Scanning Laser Ophthalmoscope.Optica, vol. 5, no. 9, Sept. 2018, pp. 1027–36. Pubmed, doi:10.1364/OPTICA.5.001027.
DuBose T, Nankivil D, LaRocca F, Waterman G, Hagan K, Polans J, Keller B, Tran-Viet D, Vajzovic L, Kuo AN, Toth CA, Izatt JA, Farsiu S. Handheld Adaptive Optics Scanning Laser Ophthalmoscope. Optica. 2018 Sep 20;5(9):1027–1036.
Journal cover image

Published In

Optica

DOI

ISSN

2334-2536

Publication Date

September 20, 2018

Volume

5

Issue

9

Start / End Page

1027 / 1036

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 1005 Communications Technologies
  • 0906 Electrical and Electronic Engineering
  • 0205 Optical Physics