Handheld adaptive optics scanning laser ophthalmoscope

Published

Journal Article

© 2018 Optical Society of America. Adaptive optics scanning laser ophthalmoscopy (AOSLO) has enabled in vivo visualization and enhanced understanding of retinal structure and function. Current generation AOSLOs have a large footprint and are mainly limited to imaging cooperative adult subjects. To extend the application of AOSLO to new patient populations, we have designed, to the best of our knowledge, the first portable handheld AOSLO (HAOSLO) system. By incorporating a novel computational wavefront sensorless AO algorithm and custom optics, we have miniaturized our HAOSLO to weigh less than 200g. HAOSLO imaged the cones closest to the fovea with a handheld probe in adults and captured, to the best of our knowledge, the first AO-enhanced image of cones in infants.

Full Text

Duke Authors

Cited Authors

  • DuBose, T; Nankivil, D; LaRocca, F; Waterman, G; Hagan, K; Polans, J; Keller, B; Tran-Viet, D; Vajzovic, L; Kuo, AN; Toth, CA; Izatt, JA; Farsiu, S

Published Date

  • September 20, 2018

Published In

Volume / Issue

  • 5 / 9

Start / End Page

  • 1027 - 1036

International Standard Serial Number (ISSN)

  • 2334-2536

Digital Object Identifier (DOI)

  • 10.1364/OPTICA.5.001027

Citation Source

  • Scopus