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Modeling environmental influences on child growth in the MAL-ED cohort study: opportunities and challenges.

Publication ,  Journal Article
Richard, SA; McCormick, BJJ; Miller, MA; Caulfield, LE; Checkley, W; MAL-ED Network Investigators,
Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
November 2014

Although genetics, maternal undernutrition and low birth weight status certainly play a role in child growth, dietary insufficiency and infectious diseases are key risk factors for linear growth faltering during early childhood. A primary goal of the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is to identify specific risk factors associated with growth faltering during the first 2 years of life; however, growth in early childhood is challenging to characterize because growth may be inherently nonlinear with age. In this manuscript, we describe some methods for analyzing longitudinal growth to evaluate both short- and long-term associations between risk factors and growth trajectories over the first 2 years of life across 8 resource-limited settings using harmonized protocols. We expect there will be enough variability within and between sites in the prevalence of risk factors and burden of linear growth faltering to allow us to distinguish some of the key pathways to linear growth faltering in the MAL-ED study.

Duke Scholars

Published In

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

DOI

EISSN

1537-6591

ISSN

1058-4838

Publication Date

November 2014

Volume

59 Suppl 4

Start / End Page

S255 / S260

Related Subject Headings

  • Models, Biological
  • Microbiology
  • Malnutrition
  • Longitudinal Studies
  • Infant, Newborn
  • Infant
  • Humans
  • Epidemiologic Research Design
  • Diarrhea
  • Child, Preschool
 

Citation

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ICMJE
MLA
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Richard, S. A., McCormick, B. J. J., Miller, M. A., Caulfield, L. E., Checkley, W., & MAL-ED Network Investigators, . (2014). Modeling environmental influences on child growth in the MAL-ED cohort study: opportunities and challenges. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 59 Suppl 4, S255–S260. https://doi.org/10.1093/cid/ciu436
Richard, Stephanie A., Benjamin J. J. McCormick, Mark A. Miller, Laura E. Caulfield, William Checkley, and William MAL-ED Network Investigators. “Modeling environmental influences on child growth in the MAL-ED cohort study: opportunities and challenges.Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America 59 Suppl 4 (November 2014): S255–60. https://doi.org/10.1093/cid/ciu436.
Richard SA, McCormick BJJ, Miller MA, Caulfield LE, Checkley W, MAL-ED Network Investigators. Modeling environmental influences on child growth in the MAL-ED cohort study: opportunities and challenges. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2014 Nov;59 Suppl 4:S255–60.
Richard, Stephanie A., et al. “Modeling environmental influences on child growth in the MAL-ED cohort study: opportunities and challenges.Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, vol. 59 Suppl 4, Nov. 2014, pp. S255–60. Epmc, doi:10.1093/cid/ciu436.
Richard SA, McCormick BJJ, Miller MA, Caulfield LE, Checkley W, MAL-ED Network Investigators. Modeling environmental influences on child growth in the MAL-ED cohort study: opportunities and challenges. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2014 Nov;59 Suppl 4:S255–S260.
Journal cover image

Published In

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

DOI

EISSN

1537-6591

ISSN

1058-4838

Publication Date

November 2014

Volume

59 Suppl 4

Start / End Page

S255 / S260

Related Subject Headings

  • Models, Biological
  • Microbiology
  • Malnutrition
  • Longitudinal Studies
  • Infant, Newborn
  • Infant
  • Humans
  • Epidemiologic Research Design
  • Diarrhea
  • Child, Preschool