Nicardipine notes: Fatal forty DDI: Nicardipine, tacrolimus, CYP3A4


Book Section

© Springer Science+Business Media New York 2015. All rights reserved. This case discusses an interaction between tacrolimus and nicardipine. Tacrolimus is a cytochrome P450 3A4 substrate and nicardipine is a 3A4 inhibitor. The interaction resulted in tacrolimus toxicity. The pharmacokinetics of nicardipine are also discussed.

Full Text

Duke Authors

Cited Authors

  • Nwazota, N; Dull, RO

Published Date

  • September 15, 2015

Book Title

  • A Case Approach to Perioperative Drug-Drug Interactions

Start / End Page

  • 569 - 571

International Standard Book Number 13 (ISBN-13)

  • 9781461474944

Digital Object Identifier (DOI)

  • 10.1007/978-1-4614-7495-1_125

Citation Source

  • Scopus