SYNTHESIS AND IN VITRO ACTIVITY OF D-LACTIC ACID OLIGOMERS
This invention describes the synthesis and pharmacologic
activity of n = 2 , n = 3 , n = 4 , n = 5 , and n = 6 D - lactic acid
oligomers . D - lactic acid dimer has pharmacologic activity
and sequesters L - lactate , and the other D - lactic acid oligom
ers have no activity in vitro , but may have pharmacologic
activity in vivo as prodrugs of D - lactic acid dimer .