SYNTHESIS AND IN VITRO ACTIVITY OF D-LACTIC ACID OLIGOMERS

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Digital Publication (Digital Edition)

This invention describes the synthesis and pharmacologic activity of n = 2 , n = 3 , n = 4 , n = 5 , and n = 6 D - lactic acid oligomers . D - lactic acid dimer has pharmacologic activity and sequesters L - lactate , and the other D - lactic acid oligom ers have no activity in vitro , but may have pharmacologic activity in vivo as prodrugs of D - lactic acid dimer .

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Duke Authors

Cited Authors

  • Goldberg, JS; Gooden, D

Published Date

  • September 27, 2018

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