The pericardium

Book Section

The pericardium is a unique structure that surrounds the heart and serves several important physiological roles. The removal of the pericardium, certain pericardial disorders, or the buildup of fluids within this space will ultimately alter hemodynamic performance. Recent therapeutic approaches have been directed to exploit the space that exists between the pericardium and the epicardial surface of the heart. New devices and techniques are being developed to access this space with minimally invasive approaches. The pharmacokinetics of many drugs may be greatly enhanced if the drug is delivered into the pericardium. As more is learned about the pericardium, it may play a significant role in cardiac therapies.

Full Text

Duke Authors

Cited Authors

  • Richardson, ES; Hill, AJ; Skadsberg, ND; Ujhelyi, M; Xiao, YF; Iaizzo, PA

Published Date

  • January 1, 2015

Book Title

  • Handbook of Cardiac Anatomy, Physiology, and Devices, Third Edition

Start / End Page

  • 163 - 174

International Standard Book Number 13 (ISBN-13)

  • 9783319194639

Digital Object Identifier (DOI)

  • 10.1007/978-3-319-19464-6_9

Citation Source

  • Scopus