The pericardium

Book Section

The pericardium is a unique structure that surrounds the heart and serves several important physiological roles; the removal of the pericardium, certain pericardial disorders, or the build-up of fluids within this space will ultimately alter hemodynamic performance. Recent therapeutic approaches have been directed to exploit the space that exists between the pericardium and the epicardial surface of the heart. New devices and techniques are being developed to access this space in a minimally invasive fashion. The pharmacokinetics of many drugs may be greatly enhanced if the drug is delivered into the pericardium. As more is learned about the pericardium, it may play a more significant role in cardiac therapies. © 2009 Humana Press.

Full Text

Duke Authors

Cited Authors

  • Richardson, ES; Hill, AJ; Skadsberg, ND; Ujhelyi, M; Xiao, YF; Iaizzo, PA

Published Date

  • December 1, 2005

Book Title

  • Handbook of Cardiac Anatomy, Physiology, and Devices: Second Edition

Start / End Page

  • 125 - 136

International Standard Book Number 13 (ISBN-13)

  • 9781588294432

Digital Object Identifier (DOI)

  • 10.1007/978-1-60327-372-5_8

Citation Source

  • Scopus