Chapter 26 - Germ Cell Tumors of the Ovary


Book Section

© 2018 Elsevier Inc. All rights reserved. Germ cell tumors of the ovary are presumed to derive from the pathogenic transformation of ovarian germ cells at different stages of development. Germ cell tumors account for 20% to 25% of all ovarian neoplasms in females. The great majority are mature teratomas, which are benign. Only 3% to 5% of all germ cell tumors in females are malignant, of which the majority are dysgerminomas, immature teratomas, and yolk sac tumors in a pure form or as part of a mixed germ cell tumor, all occurring in young patients. Somatic-type malignant transformation in mature teratoma is rare and corresponds to an additional 1% to 2% of cases; it is encountered predominantly in older patients.

Full Text

Duke Authors

Cited Authors

  • Medeiros, F; Strickland, KC

Published Date

  • December 7, 2017

Book Title

  • Diagnostic Gynecologic and Obstetric Pathology

Start / End Page

  • 949 - 1010

International Standard Book Number 13 (ISBN-13)

  • 9780323447324

Digital Object Identifier (DOI)

  • 10.1016/B978-0-323-44732-4.00026-1

Citation Source

  • Scopus