Automatic Recognition of Posed Facial Expression of Emotion in Individuals with Autism Spectrum Disorder.

Journal Article (Clinical Trial;Journal Article)

Facial expression is impaired in autism spectrum disorder (ASD), but rarely systematically studied. We focus on the ability of individuals with ASD to produce facial expressions of emotions in response to a verbal prompt. We used the Janssen Autism Knowledge Engine (JAKE®), including automated facial expression analysis software (FACET) to measure facial expressions in individuals with ASD (n = 144) and a typically developing (TD) comparison group (n = 41). Differences in ability to produce facial expressions were observed between ASD and TD groups, demonstrated by activation of facial action units (happy, scared, surprised, disgusted, but not angry or sad). Activation of facial action units correlated with parent-reported social communication skills. This approach has potential for diagnostic and response to intervention measures.Trial Registration NCT02299700.

Full Text

Duke Authors

Cited Authors

  • Manfredonia, J; Bangerter, A; Manyakov, NV; Ness, S; Lewin, D; Skalkin, A; Boice, M; Goodwin, MS; Dawson, G; Hendren, R; Leventhal, B; Shic, F; Pandina, G

Published Date

  • January 2019

Published In

Volume / Issue

  • 49 / 1

Start / End Page

  • 279 - 293

PubMed ID

  • 30298462

Electronic International Standard Serial Number (EISSN)

  • 1573-3432

Digital Object Identifier (DOI)

  • 10.1007/s10803-018-3757-9


  • eng

Conference Location

  • United States