Variability in Postarrest Targeted Temperature Management Practice: Implications of the 2015 Guidelines.

Journal Article (Journal Article)

In 2002 postarrest care was significantly altered when multiple randomized controlled trials found that therapeutic hypothermia at a goal temperature of 32-34°C significantly improved survival and neurologic outcomes. In 2013, targeted temperature management (TTM) was reexamined via a randomized controlled trial between 33°C and 36°C in post-cardiac arrest patients and found similar outcomes in both cohorts. Before the release of the 2015 American Heart Association (AHA) Guidelines, our group found that across hospitals in the United States, and even within the same institution, TTM protocol variability existed. After the 2013 TTM trial, it was anticipated that the 2015 Guidelines would clarify which target temperature should be used during postarrest care. The AHA released their updates for post-cardiac arrest TTM recently and, based on the literature available, have recommended the use of TTM at a goal temperature between 32°C and 36°C. Whether this variability has an effect on TTM implementation or patient outcomes is unknown.

Full Text

Duke Authors

Cited Authors

  • Leary, M; Blewer, AL; Delfin, G; Abella, BS

Published Date

  • December 2015

Published In

Volume / Issue

  • 5 / 4

Start / End Page

  • 184 - 187

PubMed ID

  • 26642933

Pubmed Central ID

  • PMC4677534

Electronic International Standard Serial Number (EISSN)

  • 2153-7933

Digital Object Identifier (DOI)

  • 10.1089/ther.2015.0027


  • eng

Conference Location

  • United States