Minimal data reporting standards for serological testing for histocompatibility.
Journal Article (Journal Article)
Histocompatibility testing, and HLA antibody screening in particular, varies in practice among laboratories. Currently, standards are lacking regarding the reporting of testing methods in publications. It is essential that scientific methods are rigorously and transparently described upon publication, so that results can be accurately interpreted and independently corroborated. Additionally, this would allow work groups to compile diverse data to achieve clinically significant conclusions from meta-analyses. These efforts are hindered when there is a paucity of method descriptions and where variability in serum treatment, protocol modifications, and assay thresholds affecting assay interpretation are known to exist. Thus, the ASHI Science and Technology Initiatives Committee (ASHI STIC) undertook the task of formulating recommendations for reporting HLA antibody testing by solid phase assays, and the associated HLA typing required for interpretation, in scientific publications. Herein we put forth standards for minimum information about HLA antibody testing methods reported in histocompatibility publications.
Full Text
Duke Authors
Cited Authors
- Valenzuela, NM; Askar, M; Heidt, S; Jindra, P; Madbouly, A; Pinelli, D; Jackson, A; Hidalgo, LG
Published Date
- December 2018
Published In
Volume / Issue
- 79 / 12
Start / End Page
- 865 - 868
PubMed ID
- 30125598
Electronic International Standard Serial Number (EISSN)
- 1879-1166
Digital Object Identifier (DOI)
- 10.1016/j.humimm.2018.08.008
Language
- eng
Conference Location
- United States