Fanconi Syndrome.

Journal Article (Journal Article;Review)

Fanconi syndrome, also known as the DeToni, Debré, Fanconi syndrome is a global dysfunction of the proximal tubule characterized by glucosuria, phosphaturia, generalized aminoaciduria, and type II renal tubular acidosis. Often there is hypokalemia, sodium wasting, and dehydration. In children, it typically is caused by inborn errors of metabolism, principally cystinosis. In adults, it is mainly caused by medications, exogenous toxins, and heavy metals. Treatment consists of treating the underlying cause and replacing the lost electrolytes and volume.

Full Text

Duke Authors

Cited Authors

  • Foreman, JW

Published Date

  • February 2019

Published In

Volume / Issue

  • 66 / 1

Start / End Page

  • 159 - 167

PubMed ID

  • 30454741

Electronic International Standard Serial Number (EISSN)

  • 1557-8240

Digital Object Identifier (DOI)

  • 10.1016/j.pcl.2018.09.002


  • eng

Conference Location

  • United States