Imaging and functional mapping of local circuits and epilepsy


Book Section

© 2005 by CRC Press LLC. Optical imaging (OI) is a functional imaging method that measures changes in nervous tissue light reflectance or transmission. OI has been used to study brain functions in both normal and pathophysiological states. In addition to identifying brain function in a way that is not possible with single photon emission computed tomography (SPECT), positron emission tomography (PET), and functional magnetic resonance imaging (fMRI), OI has provided a greater understanding of the physiologic mechanisms underlying these imaging methods. This chapter will present overviews of different imaging techniques, principles of optical imaging (see Figure 5.1), various studies performed at different levels of brain analysis, and finally, human open optical imaging studies.

Duke Authors

Cited Authors

  • Little, KM; Haglund, MM

Published Date

  • January 1, 2004

Book Title

  • Modern Neurosurgery: Clinical Translation of Neuroscience Advances

Start / End Page

  • 85 - 103

International Standard Book Number 10 (ISBN-10)

  • 0849314828

International Standard Book Number 13 (ISBN-13)

  • 9780849314827

Citation Source

  • Scopus