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Are Neuropeptide-Reactive T Cells behind Narcolepsy?

Publication ,  Journal Article
Deerhake, ME; Barclay, WE; Shinohara, ML
Published in: Immunity
November 20, 2018

Researchers have previously hypothesized autoimmune origins for narcolepsy on the basis of its strong genetic association with an MHC class II allele. In a recent issue of Nature, Latorre et al. (2018) discovered that narcolepsy patients had autoreactive T cells specific to the neuronal antigen hypocretin, providing more evidence of the potential immune origin of the disease.

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Published In

Immunity

DOI

EISSN

1097-4180

Publication Date

November 20, 2018

Volume

49

Issue

5

Start / End Page

796 / 798

Location

United States

Related Subject Headings

  • T-Lymphocytes
  • Orexins
  • Neuropeptides
  • Neurons
  • Narcolepsy
  • Immunology
  • Humans
  • Autoantigens
  • 3204 Immunology
  • 1107 Immunology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Deerhake, M. E., Barclay, W. E., & Shinohara, M. L. (2018). Are Neuropeptide-Reactive T Cells behind Narcolepsy? Immunity, 49(5), 796–798. https://doi.org/10.1016/j.immuni.2018.11.002
Deerhake, M Elizabeth, William E. Barclay, and Mari L. Shinohara. “Are Neuropeptide-Reactive T Cells behind Narcolepsy?Immunity 49, no. 5 (November 20, 2018): 796–98. https://doi.org/10.1016/j.immuni.2018.11.002.
Deerhake ME, Barclay WE, Shinohara ML. Are Neuropeptide-Reactive T Cells behind Narcolepsy? Immunity. 2018 Nov 20;49(5):796–8.
Deerhake, M. Elizabeth, et al. “Are Neuropeptide-Reactive T Cells behind Narcolepsy?Immunity, vol. 49, no. 5, Nov. 2018, pp. 796–98. Pubmed, doi:10.1016/j.immuni.2018.11.002.
Deerhake ME, Barclay WE, Shinohara ML. Are Neuropeptide-Reactive T Cells behind Narcolepsy? Immunity. 2018 Nov 20;49(5):796–798.
Journal cover image

Published In

Immunity

DOI

EISSN

1097-4180

Publication Date

November 20, 2018

Volume

49

Issue

5

Start / End Page

796 / 798

Location

United States

Related Subject Headings

  • T-Lymphocytes
  • Orexins
  • Neuropeptides
  • Neurons
  • Narcolepsy
  • Immunology
  • Humans
  • Autoantigens
  • 3204 Immunology
  • 1107 Immunology