© 2006 by Taylor & Francis Group, LLC. Despite improvements in surgical technique, proliferative vitreoretinopathy (PVR) remains a common and significant vision-threatening complication of retinal detachment repair and trauma. A clinically significant form of PVR occurs following approximately 5–10% of all rhegmatogenous detachment repairs (1–6). In these eyes, PVR typically develops approximately six weeks after the initial surgical repair. In eyes with established severe PVR at the time of surgery, postoperative reproliferation and redetachment occurs in up to 55% of cases (7).