INHIBITION OF BREAST CARCINOMA STEM CELL GROWTH AND METASTASIS.

Published

Journal Article

Disclosed is a method for inhibiting the growth of breast carcinoma stem cells, that express High Molecular Weight-Melanoma Associated Antigen (HMW-MAA). The method comprises administering to an individual a composition comprising an antibody reactive with HMW-MAA or a fragment of such an antibody in an amount effective to inhibit the growth of the breast carcinoma cells. Also provided are methods for inhibiting metastasis of breast carcinomas and methods for identifying HMW-MAA+ breast cancer stem cells.

Full Text

Duke Authors

Cited Authors

  • FERRONE SOLDANO, ; WANG XIANHUI, ; CLAY TIM, ; LYERLY KIM H, ; MORSE MICHAEL A, ; DEVI GAY, ; OSADA TAKUYA,

Published Date

  • September 12, 2008

Pubmed Central ID

  • PAT:MX2008011724

Language

  • eng