Randomized trial of FK 506/prednisone vs FK 506/azathioprine/prednisone after renal transplantation: preliminary report.


Conference Paper

FK 506 was used as a primary immunosuppressive agent in 125 cases of renal transplantation in a randomized trial comparing FK 506/prednisone with FK 506/azathioprine/prednisone. With a mean follow-up of 5.5 +/- 2.5 months, there has been a 6-month actuarial patient survival of 99% and graft survival of 88%. There is no difference thus far between the two-drug and three-drug groups, although there may be less rejection and diabetes in the three-drug group. These results suggest that FK 506 is a useful immunosuppressive agent in kidney transplantation.

Full Text

Duke Authors

Cited Authors

  • Shapiro, R; Jordan, ML; Scantlebury, VP; Fung, JJ; Jensen, C; Vivas, C; McCauley, J; Irish, WD; Mitchell, S; Demetris, AJ

Published Date

  • February 1993

Published In

Volume / Issue

  • 25 / 1 Pt 1

Start / End Page

  • 669 - 672

PubMed ID

  • 7679836

Pubmed Central ID

  • 7679836

International Standard Serial Number (ISSN)

  • 0041-1345

Conference Location

  • United States