Making a Tissue Microarray.

Journal Article (Journal Article;Review)

Tissue microarray (TMA) is a widely used, high-throughput, cost-effective, and tissue and reagent-conserving method of performing molecular analysis. Multiple donor tissue cores are procured and transferred into a recipient TMA block for simultaneous differential and comparative molecular profiling under theoretically identical performance conditions. Described herein is a discussion of the theory behind the TMA, an overview of the concepts and principles of TMA design and construction, a brief summary of its advantages and disadvantages, and a sample protocol of TMA construction.

Full Text

Duke Authors

Cited Authors

  • Koo, M; Squires, JM; Ying, D; Huang, J

Published Date

  • 2019

Published In

Volume / Issue

  • 1897 /

Start / End Page

  • 313 - 323

PubMed ID

  • 30539455

Electronic International Standard Serial Number (EISSN)

  • 1940-6029

Digital Object Identifier (DOI)

  • 10.1007/978-1-4939-8935-5_27


  • eng

Conference Location

  • United States