Correlation between intraocular pressure peaks in the diurnal tension curve and in the water-drinking provocative test. A study in primary open-angle glaucoma patients using timolol and dorzolamide
Purpose: To determine if the water-drinking provocative test is of value in predicting the peak of intraocular pressure (IOP) of a diurnal tension curve in patients with primary open-angle glaucoma (POAG) using timolol and dorzolamide. Methods: Thirteen patients (24 eyes) with POAG, currently using timolol and dorzolamide, were submitted to a diurnal tension curve (6h-20h) followed by a water-drinking test. We evaluated the peak of IOP in both tests. Results: There was a statistically significant correlation between the peak diurnal tension and the tension provoked by a water-drinking test (p=0.003). The difference between the two peaks was 0.25 ± 4.00mmHg, which did not differ significantly from zero. Conclusion: There is a significant correlation between the maximal IOP in the diurnal tension curve and that of a water-drinking test. This may be important in selected glaucoma patients.