Clearance from the anterior chamber of RBCs from human diabetics.

Journal Article (Journal Article)

Erythrocytes from diabetic patients manifest decreased deformability and increased adherence. These abnormal membrane properties may diminish the ability of erythrocytes (RBCs) from diabetics to undergo deformation in passage through the trabecular meshwork. Using sodium chromate Cr 51-labeled RBCs from type I diabetic patients with proliferative retinopathy and normal control subjects, we studied RBC clearance from the rabbit anterior chamber. The mean time for 50% clearance (T50) of RBCs from diabetics (76 hours) was significantly longer than that for RBCs from normal subjects (19.5 hours). In this model, RBCs from diabetics have a slower clearance from the anterior chamber than do RBCs from normal subjects.

Full Text

Duke Authors

Cited Authors

  • Williams, GA; Hatchell, DL; Collier, BD; Knobel, J

Published Date

  • June 1984

Published In

Volume / Issue

  • 102 / 6

Start / End Page

  • 930 - 931

PubMed ID

  • 6732579

International Standard Serial Number (ISSN)

  • 0003-9950

Digital Object Identifier (DOI)

  • 10.1001/archopht.1984.01040030750038


  • eng

Conference Location

  • United States