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Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management.

Publication ,  Journal Article
Previs, RA; Secord, AA
Published in: Obstet Gynecol Clin North Am
March 2019

Ovarian cancer treatment continues to evolve. Despite aggressive surgery and chemotherapy, most women will ultimately die from disease. Improvement in disease control are due to the incorporation of molecular targeted agents and the adoption of maintenance therapy. Maintenance therapy has been shown to enhance progression-free survival. Recent surgical trials have evaluated the role of neoadjuvant chemotherapy versus primary debulking at the time of diagnosis in advanced stage ovarian cancer. The role of lymph node dissection and secondary cytoreductive surgeries have also been evaluated. This article reviews contemporary trials of maintenance therapy and novel drug development.

Duke Scholars

Published In

Obstet Gynecol Clin North Am

DOI

EISSN

1558-0474

Publication Date

March 2019

Volume

46

Issue

1

Start / End Page

67 / 88

Location

United States

Related Subject Headings

  • Standard of Care
  • Patient Selection
  • Ovarian Neoplasms
  • Obstetrics & Reproductive Medicine
  • Neoadjuvant Therapy
  • Humans
  • Female
  • Cytoreduction Surgical Procedures
  • Clinical Trials as Topic
  • 4204 Midwifery
 

Citation

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Chicago
ICMJE
MLA
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Previs, R. A., & Secord, A. A. (2019). Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management. Obstet Gynecol Clin North Am, 46(1), 67–88. https://doi.org/10.1016/j.ogc.2018.09.005
Previs, Rebecca Ann, and Angeles Alvarez Secord. “Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management.Obstet Gynecol Clin North Am 46, no. 1 (March 2019): 67–88. https://doi.org/10.1016/j.ogc.2018.09.005.
Previs RA, Secord AA. Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management. Obstet Gynecol Clin North Am. 2019 Mar;46(1):67–88.
Previs, Rebecca Ann, and Angeles Alvarez Secord. “Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management.Obstet Gynecol Clin North Am, vol. 46, no. 1, Mar. 2019, pp. 67–88. Pubmed, doi:10.1016/j.ogc.2018.09.005.
Previs RA, Secord AA. Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management. Obstet Gynecol Clin North Am. 2019 Mar;46(1):67–88.
Journal cover image

Published In

Obstet Gynecol Clin North Am

DOI

EISSN

1558-0474

Publication Date

March 2019

Volume

46

Issue

1

Start / End Page

67 / 88

Location

United States

Related Subject Headings

  • Standard of Care
  • Patient Selection
  • Ovarian Neoplasms
  • Obstetrics & Reproductive Medicine
  • Neoadjuvant Therapy
  • Humans
  • Female
  • Cytoreduction Surgical Procedures
  • Clinical Trials as Topic
  • 4204 Midwifery