Synthetic Pattern Formation.


Journal Article

A fundamental question in biology is how biological patterns emerge. Because of the presence of numerous confounding factors, it is tremendously challenging to elucidate the mechanisms underlying pattern formation solely on the basis of studies of natural biological systems. Synthetic biology provides a complementary approach to investigating pattern formation by creating systems that are simpler and more controllable than their natural counterparts. In this Perspective, we summarize recent work on synthetic systems that generate spatial patterns, review the tools for building synthetic patterns, and discuss future directions of studying pattern formation with synthetic biology.

Full Text

Duke Authors

Cited Authors

  • Luo, N; Wang, S; You, L

Published Date

  • March 2019

Published In

Volume / Issue

  • 58 / 11

Start / End Page

  • 1478 - 1483

PubMed ID

  • 30666867

Pubmed Central ID

  • 30666867

Electronic International Standard Serial Number (EISSN)

  • 1520-4995

International Standard Serial Number (ISSN)

  • 0006-2960

Digital Object Identifier (DOI)

  • 10.1021/acs.biochem.8b01242


  • eng