Precision health: Advancing symptom and self-management science.

Journal Article (Journal Article)


Precision health considers individual lifestyle, genetics, behaviors, and environment context and facilitates interventions aimed at helping individuals achieve well-being and optimal health.


To present the Nursing Science Precision Health (NSPH) Model and describe the integration of precision health concepts within the domains of symptom and self-management science as reflected in the National Institute of Nursing Research P30 Centers of Excellence and P20 Exploratory Centers.


Center members developed the NSPH Model and the manuscript based on presentations and discussions at the annual NINR Center Directors Meeting and in follow-up telephone meetings.


The NSPH Model comprises four precision components (measurement; characterization of phenotype including lifestyle and environment; characterization of genotype and other biomarkers; and intervention target discovery, design, and delivery) that are underpinned by an information and data science infrastructure.


Nurse scientist leadership is necessary to realize the vision of precision health as reflected in the NSPH Model.

Full Text

Duke Authors

Cited Authors

  • Hickey, KT; Bakken, S; Byrne, MW; Bailey, DCE; Demiris, G; Docherty, SL; Dorsey, SG; Guthrie, BJ; Heitkemper, MM; Jacelon, CS; Kelechi, TJ; Moore, SM; Redeker, NS; Renn, CL; Resnick, B; Starkweather, A; Thompson, H; Ward, TM; McCloskey, DJ; Austin, JK; Grady, PA

Published Date

  • July 2019

Published In

Volume / Issue

  • 67 / 4

Start / End Page

  • 462 - 475

PubMed ID

  • 30795850

Pubmed Central ID

  • PMC6688754

Electronic International Standard Serial Number (EISSN)

  • 1528-3968

International Standard Serial Number (ISSN)

  • 0029-6554

Digital Object Identifier (DOI)

  • 10.1016/j.outlook.2019.01.003


  • eng