Precision health: Advancing symptom and self-management science.


Journal Article

BACKGROUND:Precision health considers individual lifestyle, genetics, behaviors, and environment context and facilitates interventions aimed at helping individuals achieve well-being and optimal health. PURPOSE:To present the Nursing Science Precision Health (NSPH) Model and describe the integration of precision health concepts within the domains of symptom and self-management science as reflected in the National Institute of Nursing Research P30 Centers of Excellence and P20 Exploratory Centers. METHODS:Center members developed the NSPH Model and the manuscript based on presentations and discussions at the annual NINR Center Directors Meeting and in follow-up telephone meetings. DISCUSSION:The NSPH Model comprises four precision components (measurement; characterization of phenotype including lifestyle and environment; characterization of genotype and other biomarkers; and intervention target discovery, design, and delivery) that are underpinned by an information and data science infrastructure. CONCLUSION:Nurse scientist leadership is necessary to realize the vision of precision health as reflected in the NSPH Model.

Full Text

Duke Authors

Cited Authors

  • Hickey, KT; Bakken, S; Byrne, MW; Bailey, DCE; Demiris, G; Docherty, SL; Dorsey, SG; Guthrie, BJ; Heitkemper, MM; Jacelon, CS; Kelechi, TJ; Moore, SM; Redeker, NS; Renn, CL; Resnick, B; Starkweather, A; Thompson, H; Ward, TM; McCloskey, DJ; Austin, JK; Grady, PA

Published Date

  • July 2019

Published In

Volume / Issue

  • 67 / 4

Start / End Page

  • 462 - 475

PubMed ID

  • 30795850

Pubmed Central ID

  • 30795850

Electronic International Standard Serial Number (EISSN)

  • 1528-3968

International Standard Serial Number (ISSN)

  • 0029-6554

Digital Object Identifier (DOI)

  • 10.1016/j.outlook.2019.01.003


  • eng