The birth of the Epitranscriptome: deciphering the function of RNA modifications.
Recent studies have found methyl-6-adenosine in thousands of mammalian genes, and this modification is most pronounced near the beginning of the 3' UTR. We present a perspective on current work and new single-molecule sequencing methods for detecting RNA base modifications.
Saletore, Y; Meyer, K; Korlach, J; Vilfan, ID; Jaffrey, S; Mason, CE
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