Maintenance ECT in schizophrenia: A systematic review.


Journal Article

Relapse after discontinuation of ECT is significant in patients with schizophrenia. The purpose of this systematic review was to examine use of M-ECT in schizophrenia to guide clinical decision making for relapse prevention in schizophrenia. We reviewed studies examining the role of continuation (C-ECT) and maintenance electroconvulsive therapy (M-ECT) in schizophrenia. Following PRISMA guidelines, we included randomized controlled trials, open label trials, retrospective chart reviews, case reports, and case series in this review. We evaluated adjunctive pharmacological regimens; ECT treatment parameters, including frequency, duration of continued treatment, electrode placement; clinical outcomes including cognitive side effects and relapse rates from included studies. Our findings suggest M-ECT could provide an effective form of relapse prevention in these patients and persistent cognitive side effects are minimal.

Full Text

Duke Authors

Cited Authors

  • Ward, HB; Szabo, ST; Rakesh, G

Published Date

  • June 2018

Published In

Volume / Issue

  • 264 /

Start / End Page

  • 131 - 142

PubMed ID

  • 29631245

Pubmed Central ID

  • 29631245

Electronic International Standard Serial Number (EISSN)

  • 1872-7123

Digital Object Identifier (DOI)

  • 10.1016/j.psychres.2018.03.033


  • eng

Conference Location

  • Ireland