The Burden of Childhood Atopic Dermatitis in the Primary Care Setting: A Report from the Meta-LARC Consortium.

Journal Article (Journal Article;Multicenter Study)

BACKGROUND: Little is known about the burden of atopic dermatitis (AD) encountered in US primary care practices and the frequency and type of skin care practices routinely used in children. OBJECTIVE: To estimate the prevalence of AD in children 0 to 5 years attending primary care practices in the United States and to describe routine skin care practices used in this population. DESIGN: A cross-sectional survey study of a convenience sample of children under the age of 5 attending primary care practices for any reason. SETTING: Ten primary care practices in 5 US states. RESULTS: Among 652 children attending primary care practices, the estimated prevalence of ever having AD was 24% (95% CI, 21-28) ranging from 15% among those under the age of 1 to 38% among those aged 4 to 5 years. The prevalence of comorbid asthma was higher among AD participants compared to those with no AD, namely, 12% and 4%, respectively (P < .001). Moisturizers with high water:oil ratios were most commonly used (ie, lotions) in the non-AD population, whereas moisturizers with low water:oil content (ie, ointments) were most common when AD was present. CONCLUSIONS: Our study found a large burden of AD in the primary care practice setting in the US. The majority of households reported skin care practices that may be detrimental to the skin barrier, such as frequent bathing and the routine use of moisturizers with high water: oil ratios. Clinical trials are needed to identify which skin care practices are optimal for reducing the significant burden of AD in the community.

Full Text

Duke Authors

Cited Authors

  • Al-Naqeeb, J; Danner, S; Fagnan, LJ; Ramsey, K; Michaels, L; Mitchell, J; Branca, K; Morris, C; Nease, DE; Zittleman, L; Levy, B; Daly, J; Hahn, D; Dolor, RJ; Williams, HC; Chalmers, JR; Hanifin, J; Tofte, S; Zuckerman, KE; Hansis, K; Gundersen, M; Block, J; Karr, F; Dunbrasky, S; Siebe, K; Dillon, K; Cibotti, R; Lapidus, J; Simpson, EL

Published Date

  • March 2019

Published In

Volume / Issue

  • 32 / 2

Start / End Page

  • 191 - 200

PubMed ID

  • 30850455

Electronic International Standard Serial Number (EISSN)

  • 1558-7118

Digital Object Identifier (DOI)

  • 10.3122/jabfm.2019.02.180225


  • eng

Conference Location

  • United States