Serine and Methionine Metabolism: Vulnerabilities in Lethal Prostate Cancer.
Journal Article (Journal Article)
Altered metabolism is a common feature of new and recurring malignancy. In this issue of Cancer Cell, Reina-Campos and colleagues report upregulation of the serine, glycine, one-carbon (SGOC) metabolic network is required for neuroendocrine prostate cancer, a castration-resistant aggressive form of the disease, and presents a targetable vulnerability.
Full Text
Duke Authors
Cited Authors
- Gao, X; Locasale, JW; Reid, MA
Published Date
- March 18, 2019
Published In
Volume / Issue
- 35 / 3
Start / End Page
- 339 - 341
PubMed ID
- 30889375
Pubmed Central ID
- PMC6425948
Electronic International Standard Serial Number (EISSN)
- 1878-3686
Digital Object Identifier (DOI)
- 10.1016/j.ccell.2019.02.014
Language
- eng
Conference Location
- United States