How low can you go? Achieved blood pressure and cardiovascular outcomes.

Journal Article (Journal Article)

The benefits of controlling blood pressure to levels < 140/90 mm Hg are well established, but the risks and benefits of further reductions in blood pressure are less clear. A recent observational study using pooled data from 2 large randomized trials of renin-angiotensin system blockers suggested no added benefit and some increased risk of cardiovascular events with achieved blood pressures < 120 mm Hg systolic or 70 mm Hg diastolic. Caveats of observational studies notwithstanding, these results add to the ongoing controversy over the optimal blood pressure target for high-risk individuals.

Full Text

Duke Authors

Cited Authors

  • Wyatt, CM; Cheung, AK

Published Date

  • September 2017

Published In

Volume / Issue

  • 92 / 3

Start / End Page

  • 536 - 539

PubMed ID

  • 28807258

Electronic International Standard Serial Number (EISSN)

  • 1523-1755

Digital Object Identifier (DOI)

  • 10.1016/j.kint.2017.07.002


  • eng

Conference Location

  • United States