Timing is everything? Reconciling the results of recent trials in acute kidney injury.

Journal Article (Journal Article)

Observational studies have failed to establish the optimal timing of renal replacement therapy in critically ill adults with acute kidney injury, with some studies suggesting benefit and others suggesting the potential for harm with earlier initiation. Two recent randomized trials have addressed this controversy, also with conflicting results. Careful consideration of differences between the 2 studies is essential when applying the results to clinical practice in the intensive care unit.

Full Text

Duke Authors

Cited Authors

  • Wyatt, CM; Coca, SG

Published Date

  • October 2016

Published In

Volume / Issue

  • 90 / 4

Start / End Page

  • 718 - 721

PubMed ID

  • 27575558

Electronic International Standard Serial Number (EISSN)

  • 1523-1755

International Standard Serial Number (ISSN)

  • 0085-2538

Digital Object Identifier (DOI)

  • 10.1016/j.kint.2016.07.006


  • eng